Efflux Pump AdeABC Assessment in Acinetobacter baumannii Strains Isolated in a Teaching Hospital
نویسندگان
چکیده
منابع مشابه
adeabc efflux pump genes in multidrug resistant acinetobacter baumannii isolates
conclusions adeabc efflux system plays a vital role in multidrug resistance in clinical a. baumannii isolates. it was noted that the most important gene responsible for multidrug resistance within this system was the adeb gene especially in carbapenems resistance. methods this study was conducted on 84 multidrug resistant and 13 carbapenem-susceptible a. baumannii isolates obtained from burn an...
متن کاملMultidrug resistant Acinetobacter baumannii--the role of AdeABC (RND family) efflux pump in resistance to antibiotics.
Acinetobacter baumannii is an opportunistic pathogen which play the more and more greater role in the pathogenicity of the human. It is often attached with the hospital environment, in which is able easily to survive for many days even in adverse conditions. Acinetobacter baumannii is the species responsible for a serious nosocomial infections, especially in the intensive care units. Option of ...
متن کاملResponse to Bile Salts in Clinical Strains of Acinetobacter baumannii Lacking the AdeABC Efflux Pump: Virulence Associated with Quorum Sensing
Introduction:Acinetobacter baumannii is an opportunistic nosocomial pathogen associated with multiple infections. This pathogen usually colonizes (first stage of microbial infection) host tissues that are in contact with the external environment. As one of the sites of entry in human hosts is the gastrointestinal tract, the pathogen must be capable of tolerating bile salts. However, studies ana...
متن کاملتأثیر مهارکننده‌های پمپ افلاکس بر حداقل غلظت بازدارنده بنزالکونیوم کلراید و کلرهگزیدین در جدایه‌های اسینتوباکتر بومانی جداشده از بیماران مراجعه‌کننده به بیمارستان غازی، آنکارا
Background & Aims: Today, increasing resistance to antibiotics causes serious problems for treatment of patients. The aim of this study was to determine the role of AdeABC efflux pump in the Benzalkonium chloride and Chlorhexidine MIC value with efflux pump inhibitors (1-1-naphthylmethyl-piperazine and phenyl-arginine-β-naphthylamide) in the A.baumanii strains isolated from intensive care ...
متن کاملDetection of Efflux Pump Using Ethidium Bromide-Agar Cartwheel Method in Acinetobacter baumannii Clinical Isolates
Introduction: In the past decade, multidrug-resistant Acinetobacter baumannii has become one of the most critical challenges in treating infected patients. The AdeABC efflux pump is the most important among the various resistance mechanisms. This pump can force various antibiotics and ethidium bromide out of the bacterial cell to the surrounding environment. Methods: In this study, nine A. baum...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology & Diagnosis
سال: 2016
ISSN: 2161-0703
DOI: 10.4172/2161-0703.1000237